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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60250e6123c9b79a29ca224c1709fd0c87bc20184e549157f1b6257eac0d16fb' 
  AND token = 'yi3m9Mb5Q3T4q6vY84EZg9FEIIQ73blslPkJHVh5Osc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}