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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4540e3662a3777965e5be5f8e461ba7c3326a146b2aac71669431c2850f5bb8' 
  AND token = 'hoFLXUrvpQFMgBgQrGSslakEBSyIl+lVtk/9UwkHa2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}