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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7f1dcb36e57e8318d2dde6b1b72df9773dc8ff59921762792fa4c74a75f729' 
  AND token = '0EIgtW+hFWOu6IrV7gSsK9TZE4g0SYURW3HMa4g708w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}