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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f8764064c33af6d0b6a58cd30530b215350e43f8933aea211f45f2e63f9e34' 
  AND token = 'u9u5jxjGtnV4C52oRf3ECk3I0Ds3ASBai144XZALSaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}