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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e76c3d83d8bd46b46eb2664d1b2cb068b5fa19b959082a0ff253de40afd3a786' 
  AND token = '+r7bVPb8o5/3yQPZQywG59NQ6pfcteeBoedcp2Lbt9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}