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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ef331dd3b186d41f4e4405cb7b1841db23e442028ed44ddd1cfb80f95bdba30' 
  AND token = 'KNZVIrhLWXJ+qvReSMtgbiJUs65L6iJxGWq3b2XgZpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}