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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9273e0f9cdc62b09d9a8d4c7a0e0384eaecf859665e1ba1c32f825e109e6a325' 
  AND token = 'RzFPzNpb98Pm2H2Tvt9amGlECfmTXZONx0p0deFCcLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}