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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2aeddad0eaac46c1377936b8d66792bb8b59645b34da6b7499be676cac716e' 
  AND token = '5/QWHew1R/gQFoWmtKwAzY9dJuvsibe8bT2m5z7boZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}