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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd0438b56e4039f4be65aa8111e00aa7b213d7c3c26def8ecaea962d7e6abd6' 
  AND token = 'wvJm8Tz/WETY8oN6oFRUzQ2dYLMSPwGY6/Fnf9H4X3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}