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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2bc5fc2b91dec664a0734802a773f51d08b0643bdd87157494cd5d4db3e591' 
  AND token = 'xbXF2+9xFmaw5kDsSwaMYI0OF4/t8BsR2uD4UnaSldo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}