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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8452ba049e9d87fc7a7fbbd88f7dd786a3b922a680da5d72a95c16db431948a' 
  AND token = 'gM1KrP24I8LDnz/0Jrpj0KgiluKWg/P9aleE56Xm7fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}