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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f20b080e4b0b5d916ea21d1a40e4a1c8a3d68ff5c1ee4d010836438a30b1b5' 
  AND token = '3N7OQLjgUC9+ts5UQkVJBQMqh1DOFu5U1k7qKxQYmuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}