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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf9ab3caee8ce8d7a3d19cffdedd6cdb8bbc6dd9a5babab34a66794862fc165' 
  AND token = 'ubVQqpD3g/9Sw7D/9Pdkd0EjgxaCl0katmON/yi5b1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}