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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5968c8b1a219c480a98e18d3bd90cf00247074d2f0783dc35295b16e2d7109f9' 
  AND token = '4/DqYY8bGdbveTDCDg10I2YeefD5mk3sHk/ycnOAe30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}