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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4071d0153f7509f0776537d3df884aa43f4bfef438063428dad6546f9fa546' 
  AND token = 'ZI8kKyBvt5JQSJE0mbzJk23i4F1YhJ5B1OiCOtRfVnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}