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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460fa54ef1a86e516033a5345347deb16ae26af170e48b56640ef7567bbe0376' 
  AND token = 'GpOBKqh+UdN7u2cAXAyspNFrWTjuzVLNo8u8SluaQPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}