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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59b92bdcdc3c9f79fafd41cf02033e13b1f1ce316ed595ae4c350b61272f6bb' 
  AND token = 'IHsGlZYS3+t2/z3YStwLeNIHQf9n2E9PM/lsOzWx5B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}