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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b645ea49d5c6a0d5b51dd87f14633c9dc357e2be3b693c93c00ed8017165f5de' 
  AND token = 'LGwa0ffVn8qL0WoObMKZFE6RdWf++3PsSLzKJahAmdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}