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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed8d64136189322804ea32c668f0fc65c27e14bf05b975e9e9d01298f21dcce' 
  AND token = 'ozc+Z46CWNECzQT3p3o/oSCipJ2BSl4QTxHT8EaMprg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00139

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}