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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b652799704e3027e679f6010c41d7d66d7e44ed5356fbc3d80433238b8dc1394' 
  AND token = 'NEmbEsJyZBKHAMRd42fcK0tyIybzuuh8EBTONcXXTCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}