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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c772fb6750e246715cd9a69ab1efb2bafce21c50282f3cb0709fd8d07c40759' 
  AND token = 'a2uBR8jzgdzoA1dJfsueDR6jT5emsJqzVDMXzVizd1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}