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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a18572ab80a010ac6070e00bfc37401ad68ea4a4e13def97825ccce02edaf2f6' 
  AND token = 'rsF0lFPQiU4bOkesg5FltA+cs/GeS7lKFLN4+yPIZ3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}