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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0f4ab1d14e2cd13d96757d587ebe537c2c2afe22601c5f8fcefaf02657e298' 
  AND token = 'blaYhnPjnrlGX1zTmIjMifBS+AcR0yx2ubJY2xELlns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}