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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49755f73ac1c9e63ea59ed8b3c14ed5129d73443d27f5ee8450def985d27b208' 
  AND token = 'XmbEdLHBrbtOgZyhUyh2K1rLV/jf6ScKtB+HPfUc02A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}