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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e128a1b88aa0a3ac7cc552b02edbbcd222e12d26d869c32faf1baae031fa4ff' 
  AND token = 'ugJMY43I5kvu0x60N786yRId3xmASzmJ6MVnh2prZkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}