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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c40f61c51ac0529e711fe13dd62eca4f54402905911f6f0cdfc9774f3439cad' 
  AND token = 'EAA6WkkLpREMXMCjhxdU70beZyO2gPXq6SCo7/PXmyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}