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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282c33e0b63e21da167946f61550bab67b3f3429debbdbe38624ce9904e46baa' 
  AND token = 'tweM9UlPxfbi2+3a3YF11SF2i4erYEYIUzjpjO+FrNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}