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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acdfe88a2a59140d8c59fc30c1522d0ca127731395a2d15e80594610f268bef6' 
  AND token = 'lcyOoi2FW9P8X0FbgqeWCDdwD/m29z9kTuBE7zIpQr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}