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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251813a36d495a1705095de548141863781d4981cc1be4bfbe015872c81d0a00' 
  AND token = 'ZDyHRBCZ7phrCQFUu69cSlbsPyDKyAnN+L5c8oAAo+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}