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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1496dbd9e489c86f44c6c35112f10722e2b9b938ee982ad6797bd700fe3329ff' 
  AND token = '2bK9tTPOHTm/dwQmpiAzueDdQkiU2eC/Xi8qxEYY9Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}