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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41c1b88aef419739cb2831e95bd59f9a08df615dc56850f864e41ce1bdf8afc' 
  AND token = '1v+DUtFj7VIXrZ8FIunQ61WhDLa9Q3NxPZNhmRLUssY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}