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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9816bc426cc80cda31f89ee82f5bfd73396ceb335f89deef83b03cc10b3f849b' 
  AND token = 'E997yd9DyCjoZ5F45Wa/mrqIkgMsPEh7hJVCRYUqwbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}