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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de22d9b2dbe070b6e474fc1669fdb9d5a2124027986e8e76eaaf9d3990adf896' 
  AND token = 'jb/eASZ2wivZXcHEwKUJTTZ0tYIT/BY9KCA/vnOvwFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}