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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b68c76f7b72d8b2838d41c20725271209224d314e73652e7d75eaeb3ced15bb' 
  AND token = 'bf2/lPOgiPN4BRexsN8F5yBAYRZEUVFM45HSWZ6dz+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}