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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22eb76cf332d6fb7787053ebef5c47723fcab267579e539e00f7baf2d40ac4f' 
  AND token = 'G56xHu3+zL8bOcAd1igIxBvD28/eXGQhnnbAQBFsXFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}