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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e5033f996cddc6d165daa677cf6000709904a08e6da534eea1e3e8999f2e369' 
  AND token = 'mNO/IlfiQGZqiu3EMMjs036Wggi3sbXb+iUEZ2t7JLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}