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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f74695ad51c10eb6016836ad798ffddf31ea3a4bed5f87ee8a5b193a9cd25c' 
  AND token = 'Z0VIaM+IiULLj3DlAOTBoXmXMOXJTj8kDy1xojtUrjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}