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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4efb85a17db34025622bb728f3d2c23cbaec41849058b1884c5d7ad0537a3c1d' 
  AND token = 'QrlKE0Ywal6WAnr2JRiMo+XaStJh4SnFk/UPvhvDAVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}