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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e209689a3541c98986cdad352344eade2071e9dc4a5cd894a0e959d52add1957' 
  AND token = '+/+EepiDLzxtZDVPTwXL74yU6423zpjJ9e3oYme0Axk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}