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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4f9d8a29d3aa95f8a181fcf35690eece9dcf5f4f5f2b11208832c477e85beb' 
  AND token = '+O4hqjacCaxAcbJif4RH1lAQ8YFMNS/cHXuaPjlQ0YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}