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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9db0d66bfcc6fc7cd2ac762079df40f9dec24304cfdc87d61f0d4bb9823f7d56' 
  AND token = 'DbPzd2Kiokd6U6KJwcglFWuskw1Km3rokBOKGQqfRW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}