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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c05d24c99a6e1241257834ed6a920321c1d2ebf63e4ada6ddbdb6830a478155' 
  AND token = 'Rr4mFy1mQkDdkZ9Ss+2RTUtKITaDcEyCuR4p5e03f5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}