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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac4eff1a2d719135a5d83b85d375aad273b4cb629cf9743dff135b6e1d772ae' 
  AND token = 'vhCDvavVshY+iaskyMHLj7nS5l47SwIAMFLa42wVuRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}