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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1fc4be36a0f1b584c2263c5e79e58dceb1638c5396846220a812a02807edcc' 
  AND token = '3c2TFQvQhZ0BoKJaRyl7iEvqPn70k2KkZyZFJ8qZQKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}