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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d95dbf76d364eec7bd6185b6379a9c57dedcd325897164fc7cf2adec2cc63d' 
  AND token = 'AesApJcK+lKHHzRjgYAFQbTud18JL/qNV4MW+sASLn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}