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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac43cfef1323d7ac61045e9f981cfe5fe57f310a3ea4708b03175f9b2558bd3' 
  AND token = 'iP1XQujyFWedgnph4rxStKNsS9vb8QU9tCiB5dKrMDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}