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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a081076c73b69ed3c3f904c96c3999f79aa6a25406e2c74d69f9e1f76d3db57' 
  AND token = 'fUXrusMPsrvNWdZ+Eh9srcgpgXdm/wA3A1DrmhDX4nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}