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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d606e0d841f6adf74ac214ff4a086d82914faf3283c359833f28770242254f4' 
  AND token = 'TnuHEBj3Zclo2pdkj2TCIq/NYewdF9/GOI3IxmoQZ/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}