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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36e92325c7324bb49b34c026b7a4d72bcaebacbb960b1b743a5618c7adf319b2' 
  AND token = '1maICTVQjEZ5Pg45XYGqk+UQDi1XecLfcONUPxqRxoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}