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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765c53c1677ae47f1cc89be3b62a3c493064501e6ade7ec8811e0619dfb952cc' 
  AND token = 'TVTYhiD7JWvc3/t1ShMKfu37vbeaJ2+m0LTkHS3OeBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}